Animal Care Technician – Perth, Australia
Ozgene is seeking a full-time graduate animal technician with a Bachelor of Science or certificate IV in veterinary …
Jacqui Watts – Project Coach
Jacqui became an Ozgene team member in 2002 as a Laboratory Assistant. Throughout her time at Ozgene she …
Maarit Patrick – Chief Transformation Officer
Maarit has been with Ozgene since 2003, starting as a Marketing and Sales Coordinator while also serving as …
Dr Jonathan Gauntlett – Senior Scientist
Jonathan is instrumental in guiding our team on projects from start to finish. Prior to joining Ozgene, Jonathan …
Advances in antitumour immunity
An important function of the immune system is its ability to recognise and attack foreign cells without damaging …
Sending ‘Hobit’ on a quest
In the midst of the COVID-19 pandemic, we are more aware than ever how exposed our bodies are …
COVID-19 update
With all the uncertainty of COVID-19, we hope you are safe and in good health. …
CRISPR knockout & knock-in mice
The potential of CRISPR technology is very exciting, but there are some limitations to its usefulness and drawbacks …
Insights into cancer research
Many of our customers work in the field of cancer research. We would like to share two recent …
Speed – Quality – Value
Ozgene is and has been on a journey of continuous improvement. …
Getting into “the Flow” – Yarigai – Ikigai – Lebensfreude
I was still digesting Yuval Harari’s book “Homo Deus” when I started to read Mihaly Csikszentmihalyi’s book “Flow …
Innate immunity insights
Our immune system consists of innate and adaptive subsystems working together. …
It shouldn’t be this hard by Ken Snyder
Are you struggling with Lean implementation? I’d like to share a blog by Ken Snyder that may be …
Epigenetics and the brain
Psychiatric conditions are often caused by a combination of genetic and environmental factors. …
On the road again
It doesn’t seem very long since my previous trip but I find myself on the road again. Perth …
Shedding light on EPP
While most of us enjoy a sunny day, people suffering from erythropoietic protoporphyria (EPP) have a less pleasant …
Lean – an objective or intersubjective reality?
A friend of mine asked recently: “What do you want me to present at a Lean conference?” I …
Insights into pluripotency
Embryonic Stem (ES) cells are pluripotent; they are able to develop into any cell type in an embryo …
Aloha – taking a break from Organisational Excellence
You may not know that Ozgene is a family business. I recently attended the State Conference of Family …
Cancer vaccines
Cancer vaccines are currently the focus of numerous research groups worldwide. …
Handel, Toyota and Homo Deus
I recently chaired a lunch time discussion on ‘Standard Work – the Basis for Scientific Thinking’ at the …
Revisiting Niemann-Pick Type C
Back in 2011, Ozgene created two mouse models for the Hempel family, whose twin daughters suffer from a …
Be mindful at the gemba
Over the past years we have been working on our organisational excellence framework. As a result, we have …
NO to Exercise?
Exercise is good for you. Who hasn’t heard that one before? We know about the benefits of exercise …
New Ebola research
Ebola virus disease is associated with a severe haemorrhagic fever illness with a fatality rate of up to …
Happy travelling
I’m currently travelling and meeting Lean practitioners from various industries as well as Ozgene clients. Many of our …
Novel epilepsy mouse model
Epilepsy is a collective name for a group of neurological diseases. …
Ask questions, be curious in 2017
There are questions we are asking ourselves as a company: Why? How? What? and while the order in …
Candid candidiasis research
The word ‘candida’ usually makes us think of inconvenient, yet relatively harmless fungal infections. …
Blogs of 2016
December is always a time for reflection. What happened this year? What did we achieve? What can we …
Brain search
Neurodegenerative disease refers to a range of conditions that affect the neurons in the brain. …
Response from Sensei-San
My last blog was about an exciting visit by a Lean Sensei with 40 years of experience. After …
Understanding autism
Autism Spectrum Disorder (ASD) is a lifelong neurodevelopmental disorder that first manifests in early childhood. …
Beware of kankotsu
As a keen practitioner of Lean management, the prospect of hosting a Lean Sensei with 40 years of …
The maternal brain
Physical changes in pregnancy are easily noticeable but the brain also undergoes some extraordinary modifications to prepare for …
Balancing curiosity
Last month I blogged about how to look at the world with curiosity. Why is this also important …
The epic of type 2 diabetes
Almost 90% of people with type 2 diabetes are overweight or obese. …
I can’t CU
Copper deficiency is a rare condition, sometimes caused by hereditary disorders. …
Post-it pandemonium
The humble Post-it notes have become a central part of operations here at Ozgene. They are used in …
Jacob’s role in brain signalling
The brain has an incredible ability to reorganise itself by creating new neural pathways. …
Medical Taylorism by Hartzband and Groopman
Medical Taylorism Pamela Hartzband, M.D., and Jerome Groopman, M.D. N Engl J Med 2016; 374:106-108. January 14, 2016. …
Leaning (on) our healthcare system
I usually do not reblog or comment on other people’s articles, however, the blog by Dr. Patricia Gabow …
Zinc fingers crossed
Research into the physiological functions of proteins is an extensive field of modern biomedicine. …
Jishu-what?
Our Lean philosophy is composed of two parts: people and process, the human system and the technical system. …
Breathing easy
The respiratory system has effective and complex defence mechanisms to protect itself against infections. …
Eureka moment published
This is one of those times when it’s great to be a scientist! To see your ‘Eureka moment’ …
Knock-in continues quest for diabetes cure
Diabetes is a major health challenge worldwide and understanding the disease is the focus of intensive research for …
Order within chaos
My last blog was all about ants. It touched on step changes, which allow for an increase in …
Anti-Id matters
Anti-idiotope (anti-Id) antibodies play a role in therapy against B cell lymphomas, as inhibitors of pathogenic autoantibodies, and …
Lessons from ants
Have you ever just sat and watched a colony of ants? I have… For being such small creatures, …
The heart of the matter
Heart disease is one of the most common health conditions affecting individuals across the globe. …
2015 in numbers
Another fantastic year is done and I’d like to share it with you by summarising it in numbers.
…Making a difference
Cancer research is a major focus of scientific studies worldwide. …
to advance humanity – inspire curiosity
It sounds complex and deep doesn’t it? To advance humanity – inspire curiosity. It’s what we strive for …
Varying effects of PAPP-A2
What are the genetic and physiological mechanisms that contribute to diversity within species? …
Lean journey to Shingo
Converting to Lean is a journey. Step by step we have made significant headway, specifically from a human …
Knock-in to assist brain research
Structural brain disorders are one of the most obvious causes of pathology encountered by paediatric neurologists. …
Mindfulness
If you heard the words “meditation” or “mindfulness” years ago, you probably thought of yogis or Buddhist monks. …
Mastering Mutagenesis
The world today is riddled with carcinogens and harmful mutagens ranging from the food we eat to the …
Ozgene’s Big History Project
I hope that you’ve all had a chance to watch “The Big History Project” that I introduced in …
New approaches for treating Colon Cancer
Colon cancer; now that’s a diagnosis that no one wants to hear and yet 15,000 families in Australia …
The Big History Project
Have you heard of the Big History Project? No? Well, prepare to be enlightened then. Recently, I was …
Obesity – the big and the small of it
According to the WHO, worldwide obesity has more than doubled in the past 30 years and in 2014 …
To baldly advance humanity
Well, it’s done! The hippie hair is gone and I am now sporting a new bald look just …
Mice unravel new roles for DNA caretakers
Mice make excellent models to study human medicine. …
Measuring what you manage
I believe firmly in gathering data, analysing it, and then using the information to support everything that we …
Mouse vs. Leukaemia
Did you know that mice and humans share nearly the same genetic makeup? …
I’m shaving it off!
A while back I decided to grow my hair long. It has been in a ponytail for some …
Insights into human language
Have you ever wondered how humans evolved from primates? What makes us different? …
Phenotyping – mouse making and beyond
Think of a large family where a few members have a particular illness or disease. They go …
Heart Focus
Congenital heart defects affect almost 1% of all live births. They arise from disruption of normal developmental processes, …
Lessons learnt from Clients
I’ve recently returned from one of the best business trips that I’ve had in a long time. I …
Cytoskeletal dynamics & metabolism
Discovering a lump or a bump on your body can be very concerning, as it may be the …
Growing company by growing people
At the moment I’m travelling in the US and speaking at various events, which is something I enjoy …
Fertile Considerations
Did you know that according to WHO, infertility affects up to 15% of reproductive-aged couples worldwide? …
Who said a Lean year was a bad thing?
Wow. What a year it has been. 2014 was the most successful year in Ozgene’s history. Why? How? …
Navigating Metabolism
For decades, scientists have been analyzing signaling pathways in the hope of developing effective therapies. …
Tick-tock goes the Clock
As the saying goes, "you can't manage what you don't know". This can be rephrased “you can't manage …
Brain Matters
As our population continues to age and life expectancies increase, so does the burden of neurodegenerative conditions such …
What does an F1 tyre change have to do with KO mice?
As you probably know, I have been traveling for the past two months. It was a great trip …
Joint effort on arthritis research
Inflammation is usually the body's protective response to harmful stimuli, such as injury and infection. …
The ongoing Morse quest to break the code
Most Virology and Cellular Immunology studies are mouse-based and use a wide range of experimental approaches to understand …
The Lean Ozgene story… so far
The Lean Ozgene story started as so many others, by chance. I happened to buy the book, “The …
goGermline – first time – every time
Would you like to generate knockout or knock-in mice faster and more efficiently, while improving animal welfare? Now …
Going on a globetrot for goGermline™
Following last month’s blog, I am set to embark on some more overseas travel in September and October. …
What happens when you are one of the 0.0001%?
When a disease or disorder only affects between 1 to 3 people per 1,000,000 worldwide, most don’t give …
Greetings from Japan!
That’s right, my family and I are in Japan at the moment, one of my favourite places. …
Putting the squeeze on obesity
What determines how much fat is stored on our bodies? That’s a question many people would like the …
Absolutely fabulously awesome!
That was my email to the Ozgene team this morning when they told me about the latest results. …
The new Ozgene website is a knockout!
Is there something you always wanted to know about Ozgene? Chances are that the answer can now be …
Can you see the target?
Most people take the ability to see colour for granted. This is not the case for the 8-10% …
A mouse well travelled
It was recently brought to our attention that a mouse model generated by Ozgene has become very useful …
Mouse model gives new insight into enzyme inhibiting drugs
Diabetes and cancer are some of the biggest medical concerns that we are faced with in current times. …
Joanne Deys – Executive VP Strategic Partnering
Joanne joined Ozgene in the fall of 2017 as Executive Vice President Strategic Partnering. Joanne brings with her …
Dr Roger Askew – Sr Scientific Director, North America
Roger joined the Ozgene team in May 2015 as our Senior Scientific Director in North America. He is …
Dr Frank Koentgen – Chairman & CEO
Frank is a successful entrepreneur, scientist and international biotechnology leader with …
Call Us Scent O’ Mental
We would like to congratulate Ozgene's long-term customer, Dr. Peter Mombaerts, on his recent TEDxBrussels Talk on Targeting …
What happens when you mix a little hope with curiosity?
As scientists, we are motivated by our curiosity. This curiosity can be attributed to great advances in humanity, …